UGT1A6 (基因名), UDP-glucuronosyltransferase 1-6 (蛋白名), ud16_human.
产品名称:
Human UGT1A6/ UDP-glucuronosyltransferase 1-6 CLIA Kit
货号:
U12958h
商标:
EIAab®
监管等级:
别名:
Phenol-metabolizing UDP-glucuronosyltransferase, UDP-glucuronosyltransferase 1-F, UDP-glucuronosyltransferase 1A6, UGT-1F, UDPGT 1-6, GNT1, UGT1
检测方法:
CLIA
实验类型:
Sandwich
检测范围:
19.5-1250pg/mL
特异性:
Natural and recombinant human UDP-glucuronosyltransferase 1-6
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
Metabolism
通用注释
亚单元:
Isoform 1 interacts with isoform 3/i2 suggesting that oligomerization is involved in negative regulation of transferase activity by isoform 3. Isoform 1 also interacts with respective i2 isoforms of UGT1A1, UGT1A3, UGT1A4, UGT1A7, UGT1A8, UGT1A9 and UGT1A10.
功能:
UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform has specificity for phenols. Isoform 3 lacks transferase activity but acts as a negative regulator of isoform 1.
亚细胞位置:
Microsome
Endoplasmic reticulum membrane
Single-pass membrane protein
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