VEGFA (基因名), Vascular endothelial growth factor A (蛋白名), vegfa_canlf.
产品名称:
Dog VEGFA/ Vascular endothelial growth factor A CLIA Kit
货号:
-
商标:
EIAab®
监管等级:
别名:
Vascular permeability factor, VPF, VEGF-A, VEGF
检测方法:
CLIA
特异性:
Natural and recombinant dog Vascular endothelial growth factor A
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
Cancer
通用注释
亚单元:
Homodimer; disulfide-linked. Also found as heterodimer with PGF (By similarity). Interacts with NRP1.
功能:
Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin (By similarity). Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development.
亚细胞位置:
Secreted
Secreted but remains associated to cells or to the extracellular matrix unless released by heparin.
数据库链接
UniGene:
SMR:
STRING:
KEGG:
Pfam:
Uniprot:
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