VLDLR (基因名), Very low-density lipoprotein receptor (蛋白名), vldlr_human.
产品名称:
Human VLDLR/ Very low-density lipoprotein receptor CLIA Kit
极低密度脂蛋白受体
货号:
U1009h
商标:
EIAab®
监管等级:
别名:
VLDL receptor
检测方法:
CLIA
实验类型:
Sandwich
检测范围:
109-7000pg/mL
特异性:
Natural and recombinant human Very low-density lipoprotein receptor
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
Cardiovascular
通用注释
亚单元:
Binds to the extracellular matrix protein Reelin. Interacts with VLDLR. Interacts with SNX17 (By similarity). Interacts with DAB1. Receptor for the minor-group human rhinoviruses (HRVs); binds protein VP1 through the second and third LDL-receptor class A domains. Interacts with PCSK9.
功能:
Binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. Binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation.
亚细胞位置:
Membrane
Single-pass type I membrane protein
Membrane
Clathrin-coated pit
Single-pass type I membrane protein
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