VWF (基因名), von Willebrand factor (蛋白名), vwf_canlf.
通用注释
亚单元:
Multimeric. Interacts with F8.
功能:
Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex, glycoprotein Ibalpha/IX/V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma.
亚细胞位置:
Secreted
Secreted
Extracellular space
Extracellular matrix
Localized to storage granules.
数据库链接
该产品尚未在任何出版物中被引用。
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