Bovine WASHC3/ WASH complex subunit 3 CLIA Kit

货号:

商标:

EIAab^®

监管等级:

RUO

别名:

Coiled-coil domain-containing protein 53, CCDC53

检测方法:

CLIA

特异性:

Natural and recombinant bovine WASH complex subunit 3

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

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Bovine WASHC3 CLIA Kit

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产品说明书

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通用注释

亚单元:

Component of the WASH core complex also described as WASH regulatory complex (SHRC) composed of WASHC1, WASHC2, WASHC3, WASHC4 and WASHC5 (PubMed:20498093). The WASH core complex associates via WASHC2 with the F-actin-capping protein dimer (formed by CAPZA1, CAPZA2 or CAPZA3 and CAPZB) in a transient or substoichiometric manner which was initially described as WASH complex.

功能:

Acts at least in part as component of the WASH core complex whose assembly at the surface of endosomes seems to inhibit WASH nucleation-promoting factor (NPF) activity in recruiting and activating the Arp2/3 complex to induce actin polymerization, and which is involved in regulation of the fission of tubules that serve as transport intermediates during endosome sorting.

亚细胞位置:

Early endosome

数据库链接

UniGene:

Bt.107349

STRING:

9913.ENSBTAP00000000022

KEGG:

bta:613720

Pfam:

PF10152

Uniprot: