WASF2 (基因名), Wiskott-Aldrich syndrome protein family member 2 (蛋白名), wasf2_bovin.
产品名称:
Bovine WASF2/ Wiskott-Aldrich syndrome protein family member 2 CLIA Kit
货号:
-
商标:
EIAab®
监管等级:
别名:
WASP family protein member 2
检测方法:
CLIA
特异性:
Natural and recombinant bovine Wiskott-Aldrich syndrome protein family member 2
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
-
通用注释
亚单元:
Binds actin and the Arp2/3 complex. Interacts with BAIAP2. Component of the WAVE2 complex composed of ABI1, CYFIP1/SRA1, NCKAP1/NAP1 (NCKAP1l/HEM1 in hematopoietic cells) and WASF2/WAVE2. Directly interacts with BRK1. Interacts with human cytomegalovirus protein UL135. Interacts with FNBP1L (via the SH3 domain).
功能:
Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
亚细胞位置:
Cytoplasm
Cytoskeleton
Cell projection
Lamellipodium
At the interface between the lamellipodial actin meshwork and the membrane.
数据库链接
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