WASL (基因名), Neural Wiskott-Aldrich syndrome protein (蛋白名), wasl_bovin.
产品名称:
Bovine WASL/ Neural Wiskott-Aldrich syndrome protein CLIA Kit
货号:
-
商标:
EIAab®
监管等级:
别名:
N-WASP
检测方法:
CLIA
特异性:
Natural and recombinant bovine Neural Wiskott-Aldrich syndrome protein
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
登录.
研究领域:
-
通用注释
亚单元:
Binds actin and the Arp2/3 complex. Interacts with CDC42. Binds to SH3 domains of GRB2. Interacts with the C-terminal SH3 domain of DNMBP. Interacts with the WW domains of PRPF40A/FBP11. Interacts with NOSTRIN. Binds to TNK2. Interacts with PTK2/FAK1. Interacts with PACSIN1, PACSIN2 and PACSIN3. Interacts with SNX33 (By similarity). Interacts with SNX9.
功能:
Involved in mitosis and cytokinesis, via its role in the regulation of actin polymerization (By similarity). Regulates actin polymerization by stimulating the actin-nucleating activity of the actin-related protein 2/3 (Arp2/3) complex. Binds to HSF1/HSTF1 and forms a complex on heat shock promoter elements (HSE) that negatively regulates HSP90 expression. Plays a role in dendrite spine morphogenesis.
亚细胞位置:
Nucleus
Cytoplasm
Cytoplasm
Cytoskeleton
Preferentially localized in the cytoplasm when phosphorylated and in the nucleus when unphosphorylated. Exported from the nucleus by an nuclear export signal (NES)-dependent mechanism to the cytoplasm.
数据库链接
UniGene:
SMR:
STRING:
KEGG:
Pfam:
Uniprot:
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