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Whrn (基因名), Whirlin (蛋白名), whrn_rat.
产品名称:

Rat Whrn/ Whirlin CLIA Kit

货号:

U2357r

商标:
EIAab®
监管等级:
别名:

CASK-interacting protein CIP98, Cip98, Dfnb31

检测方法:
CLIA
特异性:
Natural and recombinant rat Whirlin
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Rat Whrn CLIA Kit
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Rat Whrn CLIA Kit
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通用注释


亚单元:
Forms homooligomers (By similarity). Interacts with CASK (PubMed:12641734). Interacts (via C-terminal PDZ domain) with MYO15A; this interaction is necessary for localization of WHRN to stereocilia tips. Interacts (via C-terminal PDZ domain) with MPP1/p55. Interacts with USH2A. Interacts with LRRC4C/NGL1. Interacts with MYO7A. Interacts with RPGR. Interacts with EPS8. Interacts with GPR98/MASS1. Interacts with CIB2.


功能:
Necessary for elongation and maintenance of inner and outer hair cell stereocilia in the organ of Corti in the inner ear.


亚细胞位置:
Cytoplasm Cell projection Stereocilium Cell projection Growth cone Detected at the level of stereocilia in inner outer hair cells of the cochlea and vestibule. Colocalizes with the growing ends of actin filaments (By similarity). Colocalizes with MPP1 in the retina, at the outer limiting membrane (OLM), outer plexifirm layer (OPL), basal bodies and at the connecting cilium (CC).


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