XKR8 (基因名), XK-related protein 8 (蛋白名), xkr8_human.
通用注释
亚单元:
N/A
功能:
Promotes phosphatidylserine exposure on apoptotic cell surface, possibly by mediating phospholipid scrambling. Phosphatidylserine is a specific marker only present at the surface of apoptotic cells and acts as a specific signal for engulfment. Has no effect on calcium-induced exposure of phosphatidylserine. Activated upon caspase cleavage, suggesting that it does not act prior the onset of apoptosis.
亚细胞位置:
Cell membrane
Multi-pass membrane protein
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