Xpnpep3 (基因名), Xaa-Pro aminopeptidase 3 (蛋白名), xpp3_rat.
产品名称:
Rat Xpnpep3/ Xaa-Pro aminopeptidase 3 CLIA Kit
货号:
-
商标:
EIAab®
监管等级:
别名:
Aminopeptidase P3, APP3, X-Pro aminopeptidase 3
检测方法:
CLIA
特异性:
Natural and recombinant rat Xaa-Pro aminopeptidase 3
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
Cell Biology
通用注释
亚单元:
Homodimer. Interacts with TNFRSF1B/TNFR2 (activated) and TRAF2.
功能:
Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Leu-Pro-Ala. Also shows low activity towards peptides with Ala or Ser at the P1 position. Promotes TNFRSF1B-mediated phosphorylation of MAPK8/JNK1 and MAPK9/JNK2, suggesting a function as an adapter protein for TNFRSF1B; the effect is independent of XPNPEP3 peptidase activity. May inhibit apoptotic cell death induced via TNF-TNFRSF1B signaling.
亚细胞位置:
Mitochondrion
Cytoplasm
Mainly mitochondrial. Translocates to the cytoplasm following TNFRSF1B activation.
数据库链接
UniGene:
SMR:
STRING:
KEGG:
Pfam:
Uniprot:
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