Zbtb18 (基因名), Zinc finger and BTB domain-containing protein 18 (蛋白名), zbt18_mouse.
产品名称:
Mouse Zbtb18/ Zinc finger and BTB domain-containing protein 18 CLIA Kit
货号:
-
商标:
EIAab®
监管等级:
别名:
58 kDa repressor protein, Transcriptional repressor RP58, Zinc finger protein 238, Zfp-238, Rp58, Zfp238, Znf238
检测方法:
CLIA
特异性:
Natural and recombinant mouse Zinc finger and BTB domain-containing protein 18
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
-
通用注释
亚单元:
Interacts with DNMT3A.
功能:
Transcriptional repressor that plays a role in various developmental processes such as myogenesis and brain development. Specifically binds the consensus DNA sequence 5'-[AC]ACATCTG[GT][AC]-3' which contains the E box core, and acts by recruiting chromatin remodeling multiprotein complexes. Plays a key role in myogenesis by directly repressing the expression of ID2 and ID3, 2 inhibitors of skeletal myogenesis. Also involved in controlling cell division of progenitor cells and regulating the survival of postmitotic cortical neurons. May also play a role in the organization of chromosomes in the nucleus.
亚细胞位置:
Nucleus
Associates with condensed chromatin.
数据库链接
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