Zbtb1 (基因名), Zinc finger and BTB domain-containing protein 1 (蛋白名), zbtb1_mouse.
产品名称:
Mouse Zbtb1/ Zinc finger and BTB domain-containing protein 1 CLIA Kit
货号:
-
商标:
EIAab®
监管等级:
检测方法:
CLIA
特异性:
Natural and recombinant mouse Zinc finger and BTB domain-containing protein 1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
-
通用注释
亚单元:
Homodimer (By similarity). Homodimer (PubMed:22753936). Interacts (via BTB domain) with TRIM28 (unphosphorylated or phosphorylated form).
功能:
Acts as a transcriptional repressor (By similarity). Represses cAMP-responsive element (CRE)-mediated transcriptional activation (By similarity). In addition, has a role in translesion DNA synthesis. Requires for UV-inducible RAD18 loading, PCNA monoubiquitination, POLH recruitment to replication factories and efficient translesion DNA synthesis (By similarity). Plays a key role in the transcriptional regulation of T lymphocyte development (PubMed:22201126, PubMed:22753936).
亚细胞位置:
Nucleus
Nucleus
Nucleoplasm
Localized in dot-like structures in the nucleus. Colocalized with SMRT in nuclear bodies. The sumoylated form is preferentially located in the nucleoplasm outside the nuclear bodies (By similarity).
数据库链接
UniGene:
SMR:
STRING:
KEGG:
Pfam:
Uniprot:
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