ZHX1 (基因名), Zinc fingers and homeoboxes protein 1 (蛋白名), zhx1_human.
通用注释
亚单元:
Forms homodimers. Heterodimer (via HD1 domain) with ZHX2 (via HD1 domain). Also forms a heterodimer with ZHX3 which is a prerequisite for repressor activity. Interacts with ATF7IP and NFYA. Interacts (via homeobox domains) with DNMT3B (via PWWP domain).
功能:
Acts as a transcriptional repressor. Increases DNMT3B-mediated repressive transcriptional activity when DNMT3B is tethered to DNA. May link molecule between DNMT3B and other co-repressor proteins.
亚细胞位置:
Nucleus
Colocalized in the nucleus with DNMT3B.
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