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PRKAB1 (基因名), 5'-AMP-activated protein kinase subunit beta-1 (蛋白名), aakb1_bovin.
产品名称:

Bovine PRKAB1/ 5'-AMP-activated protein kinase subunit beta-1 ELISA Kit
5- amp活化蛋白激酶亚基-1

货号:

E1671b

商标:
EIAab®
监管等级:
别名:

AMPK subunit beta-1

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
0.78-50ng/ml
灵敏度:
0.25ng/ml
特异性:
Natural and recombinant bovine 5'-AMP-activated protein kinase subunit beta-1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
Cardiovascular
Bovine PRKAB1 ELISA Kit
规格 & 价格: cart
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Bovine PRKAB1 ELISA Kit
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


通用注释


亚单元:
AMPK is a heterotrimer of an alpha catalytic subunit (PRKAA1 or PRKAA2), a beta (PRKAB1 or PRKAB2) and a gamma non-catalytic subunits (PRKAG1, PRKAG2 or PRKAG3). Interacts with FNIP1 and FNIP2.


功能:
Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).


亚细胞位置:
N/A


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