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ADRM1 (基因名), Proteasomal ubiquitin receptor ADRM1 (蛋白名), adrm1_chick.
产品名称:

Chicken ADRM1/ Proteasomal ubiquitin receptor ADRM1 ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

Adhesion-regulating molecule 1, ARM-1

检测方法:
ELISA
特异性:
Natural and recombinant chicken Proteasomal ubiquitin receptor ADRM1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Chicken ADRM1 ELISA Kit
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Chicken ADRM1 ELISA Kit
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通用注释


亚单元:
Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP). Interacts with the proteasomal scaffolding protein PSMD1. Interacts with deubiquitinase UCHL5; this interaction activates the auto-inhibited UCHL5 by deoligomerizing it. Interacts with UBQLN2 and ubiquitin.


功能:
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. Within the complex, functions as a proteasomal ubiquitin receptor. Engages and thus activates 19S-associated deubiquitinases UCHL5 and PSMD14 during protein degradation. UCHL5 reversibly associate with the 19S regulatory particle whereas PSMD14 is an intrinsic subunit of the proteasome lid subcomplex.


亚细胞位置:
Cytoplasm Nucleus


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