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TFAP2B (基因名), Transcription factor AP-2-beta (蛋白名), ap2b_canfa.
产品名称:

Dog TFAP2B/ Transcription factor AP-2-beta ELISA Kit
转录因子AP-2-beta

货号:

E0510d

商标:
EIAab®
监管等级:
别名:

Activating enhancer-binding protein 2-beta, AP2-beta

检测方法:
ELISA
特异性:
Natural and recombinant dog Transcription factor AP-2-beta
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
Cancer
Dog TFAP2B ELISA Kit
规格 & 价格: cart
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Dog TFAP2B ELISA Kit
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通用注释


亚单元:
Binds DNA as a dimer. Can form homodimers or heterodimers with other AP-2 family members. Interacts with CITED4. Interacts with UBE2I. Interacts with KCTD1; this interaction represses transcription activation. Interacts with CITED2 (via C-terminus); the interaction stimulates TFAP2B-transcriptional activity.


功能:
Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-beta appears to be required for normal face and limb development and for proper terminal differentiation and function of renal tubular epithelia.


亚细胞位置:
Nucleus


该产品尚未在任何出版物中被引用。
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