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Arhgef1 (基因名), Rho guanine nucleotide exchange factor 1 (蛋白名), arhg1_rat.
产品名称:

Rat Arhgef1/ Rho guanine nucleotide exchange factor 1 ELISA Kit
鸟嘌呤核苷酸交换因子1

货号:

E1577r

商标:
EIAab®
监管等级:
别名:

Lbc's second cousin, Lsc

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
0.312-20ng/mL
灵敏度:
0.186ng/mL
特异性:
Natural and recombinant rat Rho guanine nucleotide exchange factor 1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
Epigenetics
Rat Arhgef1 ELISA Kit
规格 & 价格: cart
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Rat Arhgef1 ELISA Kit
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


通用注释


亚单元:
Interacts with RHOA, GNA12 and GNA13. Homooligomerizes through the coiled coil region. Interacts with CTNNAL1. May interact with CCPG1.


功能:
Seems to play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13) subunits. Acts as GTPase-activating protein (GAP) for GNA12 and GNA13, and as guanine nucleotide exchange factor (GEF) for RhoA GTPase. Activated G alpha 13/GNA13 stimulates the RhoGEF activity through interaction with the RGS-like domain. This GEF activity is inhibited by binding to activated GNA12 (By similarity). Mediates angiotensin-2-induced RhoA activation.


亚细胞位置:
Cytoplasm Membrane Translocated to the membrane by activated GNA13 or LPA stimulation.


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