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ASZ1 (基因名), Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (蛋白名), asz1_horse.
产品名称:

Horse ASZ1/ Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein, GASZ

检测方法:
ELISA
特异性:
Natural and recombinant horse Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
Cancer
Horse ASZ1 ELISA Kit
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Horse ASZ1 ELISA Kit
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亚单元:
Interacts with DDX4, PIWIL1, RANBP9 and TDRD1.


功能:
Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.


亚细胞位置:
Cytoplasm Component of the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon activity during meiosis. Specifically localizes to pi-bodies, a subset of the nuage which contains primary piRNAs (By similarity).


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