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CASP1 (基因名), Caspase-1 (蛋白名), casp1_canfa.
产品名称:

Dog CASP1/ Caspase-1 ELISA Kit
半胱天冬酶1

货号:

E1592d

商标:
EIAab®
监管等级:
别名:

Interleukin-1 beta convertase, Interleukin-1 beta-converting enzyme, p45, IL-1BC, ICE, IL-1 beta-converting enzyme, CASP-1, IL1BC

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
78-5000pg/mL
灵敏度:
20pg/mL
特异性:
Natural and recombinant dog Caspase-1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
Neurosciences
Dog CASP1 ELISA Kit
规格 & 价格: cart
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Dog CASP1 ELISA Kit
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产品说明书
数据表: 下载说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


线性
线性:给定样本通过梯度稀释,每次稀释的测量值与理论值的比值。

Sample

1:2

1:4

1:8

1:16

serum(n=5)

106-116%

106-119%

104-113%

98-107%

EDTA plasma(n=5)

100-109%

107-115%

95-105%

102-112%

heparin plasma(n=5)

96-107%

 

81-91%

105-115%

99-108%

 

通用注释


亚单元:
Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a 20 kDa (p20) and a 10 kDa (p10) subunit. The p20 subunit can also form a heterodimer with the epsilon isoform which then has an inhibitory effect. May be a component of the inflammasome, a protein complex which also includes PYCARD, CARD8 and NALP2 and whose function would be the activation of proinflammatory caspases. Interacts with CARD17/INCA and CARD18.


功能:
Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.


亚细胞位置:
Cytoplasm


该产品尚未在任何出版物中被引用。
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