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KCNIP3 (基因名), Calsenilin (蛋白名), csen_bovin.
产品名称:

Bovine KCNIP3/ Calsenilin ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

A-type potassium channel modulatory protein 3, Kv channel-interacting protein 3, KChIP3, CSEN

检测方法:
ELISA
特异性:
Natural and recombinant bovine Calsenilin
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
Cardiovascular
Bovine KCNIP3 ELISA Kit
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Bovine KCNIP3 ELISA Kit
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通用注释


亚单元:
Binds to DNA as a homomultimer. Dimerization is induced by binding to calcium. Interacts with the C-terminus of PSEN1 and PSEN2 and with PSEN2 CTF subunit. Associates with KCN1. Component of heteromultimeric potassium channels. Identified in potassium channel complexes containing KCND1, KCND2, KCND3, KCNIP1, KCNIP2, KCNIP3, KCNIP4, DPP6 and DPP10. Interacts with KCND2 and KCND3.


功能:
Calcium-dependent transcriptional repressor that binds to the DRE element of genes including PDYN and FOS. Affinity for DNA is reduced upon binding to calcium and enhanced by binding to magnesium. Seems to be involved in nociception.


亚细胞位置:
Cytoplasm Cell membrane Lipid-anchor Endoplasmic reticulum Golgi apparatus Nucleus Also membrane-bound, associated with the plasma membrane. In the presence of PSEN2 associated with the endoplasmic reticulum and Golgi. The sumoylated form is present only in the nucleus.


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