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ELOC (基因名), Elongin-C (蛋白名), eloc_bovin.
产品名称:

Bovine ELOC/ Elongin-C ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

Elongin 15 kDa subunit, RNA polymerase II transcription factor SIII subunit C, SIII p15, Transcription elongation factor B polypeptide 1, EloC, TCEB1

检测方法:
ELISA
特异性:
Natural and recombinant bovine Elongin-C
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Bovine ELOC ELISA Kit
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Bovine ELOC ELISA Kit
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产品说明书
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通用注释


亚单元:
Heterotrimer of an A (ELOA, ELOA2 or ELOA3), ELOB and ELOC subunit. The elongin BC complex interacts with EPOP; leading to recruit the elongin BC complex to Polycomb group (PcG) target genes, thereby restricting excessive activity of the PRC2/EED-EZH2 complex. Part of E3 ubiquitin ligase complexes with CUL5 or CUL2, RBX1 and a substrate adapter protein that can be either SOCS1, SOCS5, ELOA, VHL or WSB1. The elongin BC complex is part of a complex with hydroxylated HIF1A. Interacts with VHL. Interacts with TMF1. Interacts with SPSB1. posed of LIMD1, VHL, EGLN1/PHD2, ELOB and CUL2. Interacts with SPSB1. Interacts with KLHDC10; which may be an E3 ubiquitin ligase complex substrate recognition component.


功能:
The elongin BC complex seems to be involved as an adapter protein in the proteasomal degradation of target proteins via different E3 ubiquitin ligase complexes, including the von Hippel-Lindau ubiquitination complex CBC(VHL). By binding to BC-box motifs it seems to link target recruitment subunits, like VHL and members of the SOCS box family, to Cullin/RBX1 modules that activate E2 ubiquitination enzymes.


亚细胞位置:
Nucleus


该产品尚未在任何出版物中被引用。
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