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EPM2A (基因名), Laforin (蛋白名), epm2a_canfa.
产品名称:

Dog EPM2A/ Laforin ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

Lafora PTPase, LAFPTPase

检测方法:
ELISA
特异性:
Natural and recombinant dog Laforin
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Dog EPM2A ELISA Kit
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Dog EPM2A ELISA Kit
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产品说明书
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通用注释


亚单元:
Interacts with itself; interacts also with PPP1R5, HIRIP5 and EPM2AIP1. Binds polyglucosans and glycogen. Interacts with PPP1R3C. Interacts with NHLRC1/malin (via the NHL repeats). Forms a complex with NHLRC1/malin and HSP70.


功能:
Dual specificity protein phosphatase. May be involved in the control of glycogen metabolism, particularly in monitoring for and preventing the formation of poorly branched glycogen molecules (polyglucosans). Acts as a scaffold protein to facilitate PPP1R3C/PTG ubiquitination by NHLRC1/malin. Forms a complex with NHLRC1/malin and HSP70 and this complex suppresses the cellular toxicity of misfolded proteins by promoting their degradation through the ubiquitin-proteasome system (UPS).


亚细胞位置:
Cytoplasm Endoplasmic reticulum Under glycogenolytic conditions localizes to the nucleus.


该产品尚未在任何出版物中被引用。
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