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EZR (基因名), Ezrin (蛋白名), ezri_bovin.
产品名称:

Bovine EZR/ Ezrin ELISA Kit
Ezrin

货号:

E1297b

商标:
EIAab®
监管等级:
别名:

Cytovillin, Villin-2, p81, VIL2

检测方法:
ELISA
特异性:
Natural and recombinant bovine Ezrin
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
Epigenetics
Bovine EZR ELISA Kit
规格 & 价格: cart
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Bovine EZR ELISA Kit
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通用注释


亚单元:
Interacts with MPP5 and SLC9A3R2. Found in a complex with EZR, PODXL and SLC9A3R2 (By similarity). Interacts with MCC, PLEKHG6, PODXL, SCYL3/PACE1, SLC9A3R1 and TMEM8B. Interacts (when phosphorylated) with FES/FPS. Interacts with dimeric S100P, the interaction may be activating through unmasking of F-actin binding sites (By similarity). Identified in complexes that contain VIM, EZR, AHNAK, BFSP1, BFSP2, ANK2, PLEC, PRX and spectrin (By similarity). Detected in a complex composed of at least EZR, AHNAK, PPL and PRX (PubMed:14625392).


功能:
Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.


亚细胞位置:
Apical cell membrane Peripheral membrane protein Cytoplasmic side Cell projection Cell projection Microvillus membrane Peripheral membrane protein Cytoplasmic side Cell projection Ruffle membrane Peripheral membrane protein Cytoplasmic side Cytoplasm Cell cortex Cytoplasm Cytoskeleton Localization to the apical membrane of parietal cells depends on the interaction with MPP5. Localizes to cell extensions and peripheral processes of astrocytes (By similarity).


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