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HMGB1 (基因名), High mobility group protein B1 (蛋白名), hmgb1_chick.
产品名称:

Chicken HMGB1/ High mobility group protein B1 ELISA Kit
高迁移率族蛋白B1

货号:

E0399c

商标:
EIAab®
监管等级:
别名:

High mobility group protein 1, HMG-1, RCJMB04_15a21, HMG1

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
0.156-10ng/mL
灵敏度:
0.062ng/mL
特异性:
Natural and recombinant chicken High mobility group protein B1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
Epigenetics
Chicken HMGB1 ELISA Kit
规格 & 价格: cart
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Chicken HMGB1 ELISA Kit
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


通用注释


亚单元:
N/A


功能:
Multifunctional redox sensitive protein with various roles in different cellular compartments. Nuclear functions are attributed to fully reduced HGMB1. Associates with chromatin and binds DNA with a preference to non-canonical DNA structures such as single-stranded DNA, DNA-containing cruciforms or bent structures, supercoiled DNA and ZDNA. Can bent DNA and enhance DNA flexibility by looping thus providing a mechanism to promote activities on various gene promoters. Can restructure the canonical nucleosome. Proposed to be an universal biosensor for nucleic acids. May promote inflammatory response to sterile and infectious signals and may be involved in the coordination and integration of innate and adaptive immune responses. In the cytoplasm may function as sensor and/or chaperone for immunogenic nucleic acids, and mediate autophagy. May act as danger associated molecular pattern (DAMP) molecule that amplifies immune responses during tissue injury.


亚细胞位置:
Nucleus Chromosome Cytoplasm Secreted


该产品尚未在任何出版物中被引用。
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