EIAab
首页  >  酶联免疫试剂盒  >  Bovine IFNAR1 ELISA Kit
IFNAR1 (基因名), Interferon alpha/beta receptor 1 (蛋白名), inar1_bovin.
产品名称:

Bovine IFNAR1/ Interferon alpha/beta receptor 1 ELISA Kit
干扰素α/β受体1

货号:

E1425b

商标:
EIAab®
监管等级:
别名:

Type I interferon receptor 1, IFN-R-1, IFNAR

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
78-5000pg/mL
灵敏度:
25pg/mL
特异性:
Natural and recombinant bovine Interferon alpha/beta receptor 1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
Immunology
Bovine IFNAR1 ELISA Kit
规格 & 价格: cart
×
Bovine IFNAR1 ELISA Kit
邮箱 *
消息 *
Please 登录.
产品说明书
数据表: 下载说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


通用注释


亚单元:
Heterodimer with IFNAR2. Interacts with STAT1 and STAT2; the interaction requires its phosphorylation at Tyr-467. Interacts with TYK2. Interacts (serine-phosphorylated form) with FBXW11, the substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex. Interacts with SHMT2; this promotes interaction with FAM175B and the BRISC complex.


功能:
Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1 (PubMed:8318540). Functions in general as heterodimer with IFNAR2. Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta-subunits themselves (By similarity). Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway.


亚细胞位置:
Cell membrane Single-pass type I membrane protein Late endosome Lysosome Interferon binding triggers internalization of the receptor from the cell membrane into endosomes and then into lysosomes.


该产品尚未在任何出版物中被引用。
关闭
Sample Data
关闭
Sample Data
关闭
Sample Data
用户中心 close
购物车 close
我的收藏 close
我的足迹 close
清除
产品对比 close
用户中心
购物车
我的收藏
我的足迹
产品对比
回到顶部
通知
new 咨询
规格 数量 单价 (¥) 小计 1 (¥)
小计 2:
triangle
规格 数量 单价 (¥)
你想做我们的代理并得到更低的折扣吗?
请联系我们:
电话:027-59234612(+86)
传真:027-59234610(+86)
邮箱:sales@eiaab.com