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ITGA3 (基因名), Integrin alpha-3 (蛋白名), ita3_bovin.
产品名称:

Bovine ITGA3/ Integrin alpha-3 ELISA Kit

货号:

E9150b

商标:
EIAab®
监管等级:
别名:

CD49 antigen-like family member C, Galactoprotein B3, VLA-3 subunit alpha, GAPB3, CD49c

检测方法:
ELISA
特异性:
Natural and recombinant bovine Integrin alpha-3
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
Cancer
Bovine ITGA3 ELISA Kit
规格 & 价格: cart
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Bovine ITGA3 ELISA Kit
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通用注释


亚单元:
Heterodimer of an alpha and a beta subunit. The alpha subunit is composed of a heavy and a light chain linked by a disulfide bond. Alpha-3 associates with beta-1. Interacts with HPS5. Interacts with FAP (seprase); the interaction occurs at the cell surface of invadopodia membrane in a collagen-dependent manner.


功能:
Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration.


亚细胞位置:
Cell membrane Single-pass type I membrane protein Cell membrane Lipid-anchor Cell projection Invadopodium membrane Single-pass type I membrane protein Cell projection Filopodium membrane Single-pass type I membrane protein Enriched preferentially at invadopodia, cell membrane protrusions that correspond to sites of cell invasion, in a collagen-dependent manner.


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