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ITGA5 (基因名), Integrin alpha-5 (蛋白名), ita5_bovin.
产品名称:

Bovine ITGA5/ Integrin alpha-5 ELISA Kit
整合素α5

货号:

E9148b

商标:
EIAab®
监管等级:
别名:

Fibronectin receptor subunit alpha, Integrin alpha-F, VLA-5

检测方法:
ELISA
实验类型:
Sandwich
特异性:
Natural and recombinant bovine Integrin alpha-5
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
Cancer
Bovine ITGA5 ELISA Kit
规格 & 价格: cart
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Bovine ITGA5 ELISA Kit
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


通用注释


亚单元:
Heterodimer of an alpha and a beta subunit. The alpha subunit is composed of a heavy and a light chain linked by a disulfide bond. Alpha-5 associates with beta-1. Interacts with HPS5 and NISCH. Interacts with RAB21 and COMP. ITGA5:ITGB1 interacts with NOV. ITGA5:ITGB1 interacts with FBN1.


功能:
Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. ITGA5:ITGB1 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1. ITGA5:ITGB1 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1.


亚细胞位置:
Membrane Single-pass type I membrane protein Cell junction Focal adhesion Cell surface


该产品尚未在任何出版物中被引用。
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