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ITGAL (基因名), Integrin alpha-L (蛋白名), ital_bovin.
产品名称:

Bovine ITGAL/ Integrin alpha-L ELISA Kit
整合素α-L

货号:

E1572b

商标:
EIAab®
监管等级:
别名:

CD11 antigen-like family member A, Leukocyte adhesion glycoprotein LFA-1 alpha chain, Leukocyte function-associated molecule 1 alpha chain, LFA-1A, CD11a

检测方法:
ELISA
特异性:
Natural and recombinant bovine Integrin alpha-L
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
Cancer
Bovine ITGAL ELISA Kit
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通用注释


亚单元:
Heterodimer of an alpha and a beta subunit. Alpha-L associates with beta-2. Interacts with THBD.


功能:
Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrin alpha-L/beta-2 is also a receptor for F11R. Involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes. Contributes to natural killer cell cytotoxicity. Involved in leukocyte adhesion and transmigration of leukocytes including T-cells and neutrophils. Required for generation of common lymphoid progenitor cells in bone marrow, indicating the role in lymphopoiesis. Integrin alpha-L/beta-2 in association with ICAM3, contributes to apoptotic neutrophil phagocytosis by macrophages.


亚细胞位置:
Cell membrane Single-pass type I membrane protein


该产品尚未在任何出版物中被引用。
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