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ITGB1 (基因名), Integrin beta-1 (蛋白名), itb1_bovin.
产品名称:

Bovine ITGB1/ Integrin beta-1 ELISA Kit
整合素β1

货号:

E2224b

商标:
EIAab®
监管等级:
别名:

Fibronectin receptor subunit beta, VLA-4 subunit beta, CD29

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
78-5000pg/ml
灵敏度:
19pg/ml
特异性:
Natural and recombinant bovine Integrin beta-1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
Cancer
Bovine ITGB1 ELISA Kit
规格 & 价格: cart
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Bovine ITGB1 ELISA Kit
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


通用注释


亚单元:
Heterodimer of an alpha and a beta subunit. Beta-1 associates with either alpha-1, alpha-2, alpha-3, alpha-4, alpha-5, alpha-6, alpha-7, alpha-8, alpha-9, alpha-10, alpha-11 or alpha-V. Binds LGALS3BP and NMRK2, when associated with alpha-7, but not with alpha-5. Interacts with FLNA, FLNB, FLNC and RANBP9. Interacts with KRT1 in the presence of RACK1 and SRC. Interacts with JAML; integrin alpha-4/beta-1 may regulate leukocyte to endothelial cells adhesion by controlling JAML homodimerization. Alpha-V/beta-1 acts as a receptor for foot-and-mouth disease virus (FMDV). Interacts with RAB21. Interacts (via the cytoplasmic region) with RAB25 (via the hypervariable C-terminal region). Interacts with FGR and HCK. Interacts with MYO10. Interacts with DAB2. Interacts with ITGB1BP1 (via C-terminal region); the interaction is a prerequisite for focal adhesion disassembly. Interacts with FERMT2; the interaction is inhibited in presence of ITGB1BP1. Interacts with TLN1; the interaction is prevented by competitive binding of ITGB1BP1. Interacts with ACAP1; required for ITGB1 recycling. Interacts with ASAP3. Isoform 2 interacts with alpha-7A and alpha-7B in adult skeletal muscle. Isoform 2 interacts with alpha-7B in cardiomyocytes of adult heart. Interacts with seprase FAP (seprase); the interaction occurs at the cell surface of invadopodia membrane in a collagen-dependent manner. Interacts with EMP2; the interaction may be direct or indirect and ITGB1 has an heterodimer form (By similarity). ITGA5:ITGB1 interacts with NOV. ITGA4:ITGB1 is found in a ternary complex with CX3CR1 and CX3CL1. ITGA5:ITGB1 interacts with FBN1.


功能:
Isoform 2: Isoform 2 displaces isoform 1 in striated muscles.


亚细胞位置:
Isoform 2 Cell membrane Sarcolemma Cell junction In cardiac muscle, isoform 2 is found in costameres and intercalated disks.


该产品尚未在任何出版物中被引用。
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