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ITM2B (基因名), Integral membrane protein 2B (蛋白名), itm2b_bovin.
产品名称:

Bovine ITM2B/ Integral membrane protein 2B ELISA Kit

货号:

E2822b

商标:
EIAab®
监管等级:
别名:

Immature BRI2, Transmembrane protein BRI, imBRI2, Bri

检测方法:
ELISA
特异性:
Natural and recombinant bovine Integral membrane protein 2B
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
Neurosciences
Bovine ITM2B ELISA Kit
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Bovine ITM2B ELISA Kit
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通用注释


亚单元:
Homodimer; disulfide-linked. Interacts with SPPL2A and SPPL2B. Interacts with APP. Mature BRI2 (mBRI2) interacts with the APP amyloid beta A4 protein; the interaction occurs at the cell surface and in the endocytic compartments and enable alpha- and beta-secretase-induced APP cleavage inhibition. Mature BRI2 (mBRI2) interacts with the APP C99; the interaction occurs in the endocytic compartments and enable gamma-secretase-induced C99 cleavage inhibition. May form heterodimers with Bri23 peptide and APP beta-amyloid protein 40.


功能:
Bri23 peptide prevents aggregation of APP beta-amyloid protein 42 peptide into toxic oligomers.


亚细胞位置:
BRI2C, soluble form Secreted


该产品尚未在任何出版物中被引用。
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