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Kcnk18 (基因名), Potassium channel subfamily K member 18 (蛋白名), kcnki_rat.
产品名称:

Rat Kcnk18/ Potassium channel subfamily K member 18 ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

Tresk-2, Two-pore-domain potassium channel TRESK, Tresk-2, Tresk2

检测方法:
ELISA
特异性:
Natural and recombinant rat Potassium channel subfamily K member 18
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Rat Kcnk18 ELISA Kit
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Rat Kcnk18 ELISA Kit
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通用注释


亚单元:
Interacts with calcineurin. Interacts with YWHAH, in a phosphorylation-dependent manner.


功能:
Outward rectifying potassium channel. Produces rapidly activating outward rectifier K(+) currents. May function as background potassium channel that sets the resting membrane potential. Channel activity is directly activated by calcium signal. Activated by the G(q)-protein coupled receptor pathway. The calcium signal robustly activates the channel via calcineurin, whereas the anchoring of 14-3-3/YWHAH interferes with the return of the current to the resting state after activation. Inhibited also by arachidonic acid and other naturally occurring unsaturated free fatty acids. Channel activity is also enhanced by volatile anesthetics, such as isoflurane. Appears to be the primary target of hydroxy-alpha-sanshool, an ingredient of Schezuan pepper. May be involved in the somatosensory function with special respect to pain sensation.


亚细胞位置:
Cell membrane Multi-pass membrane protein


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