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Jhdm1d (基因名), Lysine-specific demethylase 7 (蛋白名), kdm7_mouse.
产品名称:

Mouse Jhdm1d/ Lysine-specific demethylase 7 ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

JmjC domain-containing histone demethylation protein 1D, Kdm7, Kiaa1718

检测方法:
ELISA
特异性:
Natural and recombinant mouse Lysine-specific demethylase 7
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Mouse Jhdm1d ELISA Kit
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Mouse Jhdm1d ELISA Kit
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通用注释


亚单元:
N/A


功能:
Histone demethylase required for brain development. Specifically demethylates dimethylated 'Lys-9' and 'Lys-27' (H3K9me2 and H3K27me2, respectively) of histone H3 and monomethylated histone H4 'Lys-20' residue (H4K20Me1), thereby playing a central role in histone code. Specifically binds trimethylated 'Lys-4' of histone H3 (H3K4me3), affecting histone demethylase specificity: in presence of H3K4me3, it has no demethylase activity toward H3K9me2, while it has high activity toward H3K27me2. Demethylates H3K9me2 in absence of H3K4me3. Has activity toward H4K20Me1 only when nucleosome is used as a substrate and when not histone octamer is used as substrate.


亚细胞位置:
Nucleus


该产品尚未在任何出版物中被引用。
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