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Lhfpl4 (基因名), LHFPL tetraspan subfamily member 4 protein (蛋白名), lhpl4_rat.
产品名称:

Rat Lhfpl4/ LHFPL tetraspan subfamily member 4 protein ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

Lipoma HMGIC fusion partner-like 4 protein

检测方法:
ELISA
特异性:
Natural and recombinant rat LHFPL tetraspan subfamily member 4 protein
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Rat Lhfpl4 ELISA Kit
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Rat Lhfpl4 ELISA Kit
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通用注释


亚单元:
Interacts with GABA(A) receptor subunits (PubMed:28279354). Interacts with GABRB3 (By similarity). Interacts with GABRA2 (By similarity). Interacts with GABRG2 (By similarity). Interacts with GABRA1 (PubMed:28279354). Identified in a complex of 720 kDa composed of LHFPL4, NLGN2, GABRA1, GABRB2, GABRG2 and GABRB3 (PubMed:28279354). Interacts with NLGN2; leading to mutual regulation of protein level and synaptic clustering (By similarity).


功能:
Plays a role in the regulation of inhibitory synapse formation and function by being involved in maintening gamma-aminobutyric acid receptors (GABAARs) clustering and their associated scaffold proteins at inhibitory synaptic sites. Acts in concert with NLGN2 to recruit or stabilize GABAARs.


亚细胞位置:
Cell projection Dendrite Cell junction Synapse Postsynaptic cell membrane Multi-pass membrane protein Specifically localizes to inhibitory postsynaptic sites (PubMed:29742426). Colocalizes with GPHN, GABRG2 and NLGN2 at inhibitory postsynaptic sites (PubMed:29742426, PubMed:28978485).


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