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Mapre1 (基因名), Microtubule-associated protein RP/EB family member 1 (蛋白名), mare1_rat.
产品名称:

Rat Mapre1/ Microtubule-associated protein RP/EB family member 1 ELISA Kit
微管相关蛋白RP/EB家族成员1

货号:

E2190r

商标:
EIAab®
监管等级:
别名:

APC-binding protein EB1, End-binding protein 1, EB1

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
0.156-10ng/mL
灵敏度:
0.091ng/mL
特异性:
Natural and recombinant rat Microtubule-associated protein RP/EB family member 1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
-
Rat Mapre1 ELISA Kit
规格 & 价格: cart
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Rat Mapre1 ELISA Kit
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产品说明书
数据表: 下载说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


通用注释


亚单元:
Homodimer. Heterodimer with MAPRE3. Interacts with DCTN1, DCTN2, DIAPH1, DIAPH2, TERF1 and dynein intermediate chain. Interacts with APC (via C-terminal domain), CLASP2, DST, KIF2C and STIM1; probably required for their targeting to the growing microtubule plus ends. Interacts with MTUS2; interaction is direct and probably targets MTUS2 to microtubules. Interacts with APC2. Interacts with CLASP1 (By similarity). According to PubMed:19553473, MAPRE1 does not interact with CDK5RAP2 (By similarity). Interacts with MACF1. Interacts (via C-terminus) with CLIP1. Interacts with SLAIN (By similarity). Interacts with KIF18B; this interaction is required for efficient accumulation of KIF18B at microtubule plus ends (By similarity). Interacts with MISP (By similarity). Interacts with KCNAB2 (PubMed:21357749) Interacts with RABL2/RABL2A; binds preferentially to GTP-bound RABL2. Interacts with KNSTRN. Interacts with NCKAP5L.


功能:
Binds to the plus end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes cytoplasmic microtubule nucleation and elongation. May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration.


亚细胞位置:
Cytoplasm Cytoplasm Cytoskeleton Cytoplasm Cytoskeleton Microtubule organizing center Centrosome Associated with the microtubule network at the growing distal tip of microtubules. Detected along microtubules. Also enriched at the centrosome (By similarity).


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