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MVP (基因名), Major vault protein (蛋白名), mvp_bovin.
产品名称:

Bovine MVP/ Major vault protein ELISA Kit
库主要蛋白质

货号:

E1071b

商标:
EIAab®
监管等级:
别名:

MVP

检测方法:
ELISA
特异性:
Natural and recombinant bovine Major vault protein
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Bovine MVP ELISA Kit
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Bovine MVP ELISA Kit
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通用注释


亚单元:
The vault ribonucleoprotein particle is a huge (400 A x 670 A) cage structure of 12.9 MDa. It consists of a dimer of half-vaults, with each half-vault comprising 39 identical major vault protein (MVP) chains, PARP4 and one or more vault RNAs (vRNAs). Interacts with TEP1. Interacts with PTEN and activated MAPK1. The phosphorylated protein interacts with the SH2 domains of PTPN11 and SRC. Interacts with APEX1. May interact with ZNF540.


功能:
Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport. Down-regulates IFNG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases.


亚细胞位置:
Cytoplasm Nucleus


该产品尚未在任何出版物中被引用。
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