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Nr0b2 (基因名), Nuclear receptor subfamily 0 group B member 2 (蛋白名), nr0b2_rat.
产品名称:

Rat Nr0b2/ Nuclear receptor subfamily 0 group B member 2 ELISA Kit

货号:

E16127r

商标:
EIAab®
监管等级:
别名:

Orphan nuclear receptor SHP, Small heterodimer partner, Shp

检测方法:
ELISA
特异性:
Natural and recombinant rat Nuclear receptor subfamily 0 group B member 2
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
Cardiovascular
Rat Nr0b2 ELISA Kit
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Rat Nr0b2 ELISA Kit
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产品说明书
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通用注释


亚单元:
Heterodimer; efficient DNA binding requires dimerization with another bHLH protein. Interacts (via N-terminus) with NEUROD1 (via N-terminus an C-terminus). Interacts with ID2. Interacts with NR1I3 and EID1 (By similarity). Interacts with RARA, RXRA, THRB, NR5A1, NR5A2, PPARA and PPARG. May also interact with HNF4A.


功能:
Acts as a transcriptional regulator. Acts as a negative regulator of receptor-dependent signaling pathways. Specifically inhibits transactivation of the nuclear receptor with whom it interacts. Inhibits transcriptional activity of NEUROD1 on E-box-containing promoter by interfering with the coactivation function of the p300/CBP-mediated transcription complex for NEUROD1.


亚细胞位置:
Cytoplasm Nucleus Colocalizes with NEUROD1 in the nucleus.


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