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OARD1 (基因名), ADP-ribose glycohydrolase OARD1 (蛋白名), oard1_bovin.
产品名称:

Bovine OARD1/ ADP-ribose glycohydrolase OARD1 ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

O-acetyl-ADP-ribose deacetylase 1, Terminal ADP-ribose protein glycohydrolase 1, [Protein ADP-ribosylglutamate] hydrolase OARD1

检测方法:
ELISA
特异性:
Natural and recombinant bovine ADP-ribose glycohydrolase OARD1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Bovine OARD1 ELISA Kit
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Bovine OARD1 ELISA Kit
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亚单元:
N/A


功能:
ADP-ribose glycohydrolase that hydrolyzes ADP-ribose and acts on different substrates, such as proteins ADP-ribosylated on glutamate and O-acetyl-ADP-D-ribose. Specifically acts as a glutamate mono-ADP-ribosylhydrolase by mediating the removal of mono-ADP-ribose attached to glutamate residues on proteins. Does not act on poly-ADP-ribosylated proteins: the poly-ADP-ribose chain of poly-ADP-ribosylated glutamate residues must by hydrolyzed into mono-ADP-ribosylated glutamate by PARG to become a substrate for OARD1. Deacetylates O-acetyl-ADP ribose, a signaling molecule generated by the deacetylation of acetylated lysine residues in histones and other proteins. Catalyzes the deacylation of O-acetyl-ADP-ribose, O-propionyl-ADP-ribose and O-butyryl-ADP-ribose, yielding ADP-ribose plus acetate, propionate and butyrate, respectively.


亚细胞位置:
Nucleus Nucleoplasm Nucleus Nucleolus Chromosome Localizes both in the nucleoplasm and in the nucleolus. Relocalizes to the nucleoplasm in response to DNA damage. Recruited to DNA lesion regions following DNA damage.


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