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Oasl2 (基因名), 2'-5'-oligoadenylate synthase-like protein 2 (蛋白名), oasl2_mouse.
产品名称:

Mouse Oasl2/ 2'-5'-oligoadenylate synthase-like protein 2 ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

54 kDa 2'-5'-oligoadenylate synthase-like protein, M1204, p54 OASL

检测方法:
ELISA
特异性:
Natural and recombinant mouse 2'-5'-oligoadenylate synthase-like protein 2
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Mouse Oasl2 ELISA Kit
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Mouse Oasl2 ELISA Kit
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亚单元:
N/A


功能:
Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. Synthesizes oligomers of 2'-5'-oligoadenylates (2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L (RNase L) leading to its dimerization and subsequent activation. Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the inhibition of protein synthesis, thus terminating viral replication. Can mediate the antiviral effect via the classical RNase L-dependent pathway or an alternative antiviral pathway independent of RNase L.


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