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Obsl1 (基因名), Obscurin-like protein 1 (蛋白名), obsl1_rat.
产品名称:

Rat Obsl1/ Obscurin-like protein 1 ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
检测方法:
ELISA
特异性:
Natural and recombinant rat Obscurin-like protein 1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Rat Obsl1 ELISA Kit
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Rat Obsl1 ELISA Kit
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产品说明书
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通用注释


亚单元:
Component of the 3M complex, composed of core components CUL7, CCDC8 and OBSL1. Interacts with CCDC8. Interacts with CUL7; the interaction is direct. Interacts with FBXW8. Interacts (via N-terminal Ig-like domain) with TTN/titin (via C-terminal Ig-like domain); the interaction is direct.


功能:
Core component of the 3M complex, a complex required to regulate microtubule dynamics and genome integrity. It is unclear how the 3M complex regulates microtubules, it could act by controlling the level of a microtubule stabilizer (By similarity). Acts as a regulator of the Cul7-RING(FBXW8) ubiquitin-protein ligase, playing a critical role in the ubiquitin ligase pathway that regulates Golgi morphogenesis and dendrite patterning in brain. Required to localize CUL7 to the Golgi apparatus in neurons.


亚细胞位置:
Cytoplasm Cytoplasm Perinuclear region Golgi apparatus Colocalizes with CUL7 at the Golgi apparatus in neurons.


该产品尚未在任何出版物中被引用。
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