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OPRL1 (基因名), Nociceptin receptor (蛋白名), oprx_pig.
产品名称:

Pig OPRL1/ Nociceptin receptor ELISA Kit
孤啡肽受体

货号:

E9791p

商标:
EIAab®
监管等级:
别名:

K3 opiate receptor, Kappa-type 3 opioid receptor, ORGC, Orphanin FQ receptor, KOR-3

检测方法:
ELISA
特异性:
Natural and recombinant pig Nociceptin receptor
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Pig OPRL1 ELISA Kit
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通用注释


亚单元:
N/A


功能:
G-protein coupled opioid receptor that functions as receptor for the endogenous neuropeptide nociceptin. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling via G proteins mediates inhibition of adenylate cyclase activity and calcium channel activity. Arrestins modulate signaling via G proteins and mediate the activation of alternative signaling pathways that lead to the activation of MAP kinases. Plays a role in modulating nociception and the perception of pain. Plays a role in the regulation of locomotor activity by the neuropeptide nociceptin.


亚细胞位置:
Cell membrane Multi-pass membrane protein Cytoplasmic vesicle Ligand binding leads to receptor internalization into cytoplasmic vesicles, decreasing the amount of available receptor at the cell surface. Internalization requires phosphorylation at Ser-363. Can recycle to the cell membrane (By similarity).


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