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OSTC (基因名), Oligosaccharyltransferase complex subunit OSTC (蛋白名), ostc_canlf.
产品名称:

Dog OSTC/ Oligosaccharyltransferase complex subunit OSTC ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
检测方法:
ELISA
特异性:
Natural and recombinant dog Oligosaccharyltransferase complex subunit OSTC
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Dog OSTC ELISA Kit
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Dog OSTC ELISA Kit
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通用注释


亚单元:
May be an accessory component of the STT3A-containing form of the oligosaccharyltransferase (OST) complex. OST exists in two different complex forms which contain common core subunits RPN1, RPN2, OST48, OST4, DAD1 and TMEM258, either STT3A or STT3B as catalytic subunits, and form-specific accessory subunits. OST can form stable complexes with the Sec61 complex or with both the Sec61 and TRAP complexes. Interacts with PSEN1 and NCSTN; indicative for an association with the gamma-secretase complex.


功能:
May act as substrate-specific component of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. May be involved in N-glycosylation of APP (beta-amyloid precursor protein). Can modulate gamma-secretase cleavage of APP by enhancing endoprotelysis of PSEN1.


亚细胞位置:
Endoplasmic reticulum Membrane Multi-pass membrane protein


该产品尚未在任何出版物中被引用。
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