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Otop1 (基因名), Proton channel OTOP1 (蛋白名), otop1_rat.
产品名称:

Rat Otop1/ Proton channel OTOP1 ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

Otopetrin-1

检测方法:
ELISA
特异性:
Natural and recombinant rat Proton channel OTOP1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Rat Otop1 ELISA Kit
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Rat Otop1 ELISA Kit
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通用注释


亚单元:
N/A


功能:
Proton-selective channel that specifically transports protons into cells. Proton channel activity is only weakly-sensitive to voltage. Proton-selective channel activity is probably required in cell types that use changes in intracellular pH for cell signaling or to regulate biochemical or developmental processes. In the vestibular system of the inner ear, required for the formation and function of otoconia, which are calcium carbonate crystals that sense gravity and acceleration. Probably acts by maintaining the pH appropriate for formation of otoconia. Regulates purinergic control of intracellular calcium in vestibular supporting cells. May be involved in sour taste perception in sour taste cells by mediating entry of protons within the cytosol. Also involved in energy metabolism, by reducing adipose tissue inflammation and protecting from obesity-induced metabolic dysfunction.


亚细胞位置:
Cell membrane Multi-pass membrane protein Detected in the gelatinous membrane overlying the inner ear macular epithelium.


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