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PEAK1 (基因名), Inactive tyrosine-protein kinase PEAK1 (蛋白名), peak1_human.
产品名称:

Human PEAK1/ Inactive tyrosine-protein kinase PEAK1 ELISA Kit
无活性酪氨酸蛋白激酶峰值1

货号:

E15408h

商标:
EIAab®
监管等级:
别名:

Pseudopodium-enriched atypical kinase 1, Sugen kinase 269, Tyrosine-protein kinase SgK269, KIAA2002

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
78-5000pg/mL
灵敏度:
24pg/mL
特异性:
Natural and recombinant human Inactive tyrosine-protein kinase PEAK1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
-
Human PEAK1 ELISA Kit
规格 & 价格: cart
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Human PEAK1 ELISA Kit
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产品说明书
数据表: 下载说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


通用注释


亚单元:
Homodimer (PubMed:29212708). Interacts with BCAR1 and CRK (PubMed:20534451). Interacts with PRAG1 (PubMed:29079850). Interacts (when phosphorylated at Tyr-1188) with SHC1 (via PID domain) (PubMed:23846654). Found in a complex with PPP1CA, PPP1CC, SHC1 and PEAK1.


功能:
Probable catalytically inactive kinase. Scaffolding protein that regulates the cytoskeleton to control cell spreading and migration by modulating focal adhesion dynamics (PubMed:23105102, PubMed:20534451). Acts as a scaffold for mediating EGFR signaling (PubMed:23846654).


亚细胞位置:
Cytoplasm Cytoskeleton Cell junction Focal adhesion Colocalizes with F-actin in serum-rich medium (PubMed:20534451). Actin colocalization is reduced during serum starvation (PubMed:20534451).


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