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PLD6 (基因名), Mitochondrial cardiolipin hydrolase (蛋白名), pld6_canfa.
产品名称:

Dog PLD6/ Mitochondrial cardiolipin hydrolase ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

Choline phosphatase 6, Mitochondrial phospholipase, Phosphatidylcholine-hydrolyzing phospholipase D6, Phospholipase D6, MitoPLD, PLD 6

检测方法:
ELISA
特异性:
Natural and recombinant dog Mitochondrial cardiolipin hydrolase
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Dog PLD6 ELISA Kit
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Dog PLD6 ELISA Kit
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产品说明书
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通用注释


亚单元:
Homodimer.


功能:
Cardiolipin hydrolase present at the mitochondrial outer membrane required both for mitochondrial fusion and piRNA metabolic process. Acts by catalyzing the hydrolysis of cardiolipin (diphosphatidylglycerol) to form phosphatidate (phosphatidic acid or PA) at the mitochondrial outer membrane surface, promoting mitochondrial fusion. The production of phosphatidate also regulates the piRNA metabolic process by promoting recruitment and/or activation of components of the meiotic nuage, also named P granule, a critical step for primary biogenesis of piRNAs. Required during spermatogenesis to repress transposable elements and prevent their mobilization via its role in the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons.


亚细胞位置:
Mitochondrion outer membrane Single-pass membrane protein


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