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PPARGC1A (基因名), Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (蛋白名), prgc1_bovin.
产品名称:

Bovine PPARGC1A/ Peroxisome proliferator-activated receptor gamma coactivator 1-alpha ELISA Kit
PGC-1-alpha

货号:

E1160b

商标:
EIAab®
监管等级:
别名:

PGC-1-alpha, PGC1, PGC1A, PPARGC1

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
0.312-20ng/ml
灵敏度:
0.097ng/ml
特异性:
Natural and recombinant bovine Peroxisome proliferator-activated receptor gamma coactivator 1-alpha
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
Neurosciences
Bovine PPARGC1A ELISA Kit
规格 & 价格: cart
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Bovine PPARGC1A ELISA Kit
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产品说明书
数据表: 下载说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


通用注释


亚单元:
Homooligomer. Interacts with MYBBP1A; inhibits MYBBP1A transcriptional activation. Interacts with PRDM16, LPIN1 and PML. Interacts (via LXXLL motif) with RORA and RORC (via AF-2 motif); activates RORA and RORC transcriptional activation. Interacts with LRPPRC. Interacts with RNF34 (via RING-type zinc finger).


功能:
Transcriptional coactivator for steroid receptors and nuclear receptors. Greatly increases the transcriptional activity of PPARG and thyroid hormone receptor on the uncoupling protein promoter. Can regulate key mitochondrial genes that contribute to the program of adaptive thermogenesis. Plays an essential role in metabolic reprogramming in response to dietary availability through coordination of the expression of a wide array of genes involved in glucose and fatty acid metabolism. Induces the expression of PERM1 in the skeletal muscle in an ESRRA-dependent manner. Also involved in the integration of the circadian rhythms and energy metabolism. Required for oscillatory expression of clock genes, such as ARNTL/BMAL1 and NR1D1, through the coactivation of RORA and RORC, and metabolic genes, such as PDK4 and PEPCK.


亚细胞位置:
Nucleus Nucleus PML body


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