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POLR3F (基因名), DNA-directed RNA polymerase III subunit RPC6 (蛋白名), rpc6_bovin.
产品名称:

Bovine POLR3F/ DNA-directed RNA polymerase III subunit RPC6 ELISA Kit

货号:

E6230b

商标:
EIAab®
监管等级:
别名:

DNA-directed RNA polymerase III subunit F, RNA polymerase III subunit C6

检测方法:
ELISA
特异性:
Natural and recombinant bovine DNA-directed RNA polymerase III subunit RPC6
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Bovine POLR3F ELISA Kit
规格 & 价格: cart
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Bovine POLR3F ELISA Kit
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产品说明书
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通用注释


亚单元:
Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits. RPC3/POLR3C, RPC6/POLR3F and RPC7/POLR3G form a Pol III subcomplex. Interacts with TBP and TFIIIB90 and GTF3C4.


功能:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. May direct RNA Pol III binding to the TFIIIB-DNA complex. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts induce type I interferon and NF- Kappa-B through the RIG-I pathway.


亚细胞位置:
Nucleus


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