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SCN10A (基因名), Sodium channel protein type 10 subunit alpha (蛋白名), scnaa_canfa.
产品名称:

Dog SCN10A/ Sodium channel protein type 10 subunit alpha ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

NaNG, Sodium channel protein type X subunit alpha, Voltage-gated sodium channel subunit alpha Nav1.8

检测方法:
ELISA
特异性:
Natural and recombinant dog Sodium channel protein type 10 subunit alpha
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Dog SCN10A ELISA Kit
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Dog SCN10A ELISA Kit
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亚单元:
The voltage-resistant sodium channel consists of an ion conducting pore forming alpha-subunit regulated by one or more associated auxiliary subunits SCN1B, SCN2B and SCN3B. Found in a number of complexes with PRX, DYNLT1 and PDZD2. Interacts with proteins such as FSTL1, PRX, DYNLT1, PDZD2, S100A10 and many others (By similarity). Interacts with NEDD4 and NEDD4L.


功能:
This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which sodium ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-resistant sodium channel isoform. Its electrophysiological properties vary depending on the type of the associated beta subunits (in vitro). Plays a role in neuropathic pain mechanisms.


亚细胞位置:
Membrane Multi-pass membrane protein It can be translocated to the extracellular membrane through association with S100A10.


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