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Acaa2 (基因名), 3-ketoacyl-CoA thiolase, mitochondrial (蛋白名), thim_rat.
产品名称:

Rat Acaa2/ 3-ketoacyl-CoA thiolase, mitochondrial ELISA Kit

货号:

E16216r

商标:
EIAab®
监管等级:
别名:

Acetyl-CoA acetyltransferase, Acetyl-CoA acyltransferase, Acyl-CoA hydrolase, mitochondrial, Beta-ketothiolase, Mitochondrial 3-oxoacyl-CoA thiolase

检测方法:
ELISA
特异性:
Natural and recombinant rat 3-ketoacyl-CoA thiolase, mitochondrial
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Rat Acaa2 ELISA Kit
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Rat Acaa2 ELISA Kit
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通用注释


亚单元:
Homotetramer. Interacts with BNIP3 (By similarity).


功能:
In the production of energy from fats, this is one of the enzymes that catalyzes the last step of the mitochondrial beta-oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA (Probable). Using free coenzyme A/CoA, catalyzes the thiolytic cleavage of medium- to long-chain unbranched 3-oxoacyl-CoAs into acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms (Probable). Also catalyzes the condensation of two acetyl-CoA molecules into acetoacetyl-CoA and could be involved in the production of ketone bodies (Probable). Also displays hydrolase activity on various fatty acyl-CoAs (PubMed:16476568). Thereby, could be responsible for the production of acetate in a side reaction to beta-oxidation (Probable). Abolishes BNIP3-mediated apoptosis and mitochondrial damage (By similarity).


亚细胞位置:
Mitochondrion


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