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TMPRSS2 (基因名), Transmembrane protease serine 2 (蛋白名), tmps2_human.
产品名称:

Human TMPRSS2/ Transmembrane protease serine 2 ELISA Kit
跨膜蛋白酶丝氨酸2

货号:

E9842h

商标:
EIAab®
监管等级:
别名:

Serine protease 10, PRSS10

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
78-5000pg/ml
灵敏度:
36.5pg/ml
特异性:
Natural and recombinant human Transmembrane protease serine 2
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
Cancer
Human TMPRSS2 ELISA Kit
规格 & 价格: cart
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Human TMPRSS2 ELISA Kit
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产品说明书
数据表: 下载说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


通用注释


亚单元:
The catalytically active form interacts with ACE2.


功能:
Serine protease that proteolytically cleaves and activates the viral spike glycoproteins which facilitate virus-cell membrane fusions; spike proteins are synthesized and maintained in precursor intermediate folding states and proteolysis permits the refolding and energy release required to create stable virus-cell linkages and membrane coalescence. Facilitates human SARS coronavirus (SARS-CoV) infection via two independent mechanisms, proteolytic cleavage of ACE2, which might promote viral uptake, and cleavage of coronavirus spike glycoprotein which activates the glycoprotein for cathepsin L-independent host cell entry. Proteolytically cleaves and activates the spike glycoproteins of human coronavirus 229E (HCoV-229E) and human coronavirus EMC (HCoV-EMC) and the fusion glycoproteins F0 of Sendai virus (SeV), human metapneumovirus (HMPV), human parainfluenza 1, 2, 3, 4a and 4b viruses (HPIV). Essential for spread and pathogenesis of influenza A virus (strains H1N1, H3N2 and H7N9); involved in proteolytic cleavage and activation of hemagglutinin (HA) protein which is essential for viral infectivity.


亚细胞位置:
Transmembrane protease serine 2 catalytic chain Secreted Activated by cleavage and secreted.


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