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U2AF1L4 (基因名), Splicing factor U2AF 26 kDa subunit (蛋白名), u2af4_bovin.
产品名称:

Bovine U2AF1L4/ Splicing factor U2AF 26 kDa subunit ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

U2 small nuclear RNA auxiliary factor 1-like protein 4, U2AF1-like 4

检测方法:
ELISA
特异性:
Natural and recombinant bovine Splicing factor U2AF 26 kDa subunit
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
Cancer
Bovine U2AF1L4 ELISA Kit
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Bovine U2AF1L4 ELISA Kit
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产品说明书
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通用注释


亚单元:
Interacts with GFI1, U2AF2 and C1QBP.


功能:
RNA-binding protein that function as a pre-mRNA splicing factor. Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Acts by enhancing the binding of U2AF2 to weak pyrimidine tracts. Also participates in the regulation of alternative pre-mRNA splicing. Activates exon 5 skipping of PTPRC during T-cell activation; an event reversed by GFI1. Binds to RNA at the AG dinucleotide at the 3'-splice site (By similarity). Shows a preference for AGC or AGA.


亚细胞位置:
Nucleus Nucleus speckle Cytoplasm Interaction with C1QBP is required for the nuclear translocation. Displays active nucleo-cytoplasmic shuttling.


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